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Central Florida HIFU Care | Prostate Cancer Treatment


1. What is the history of HIFU and how long has it been done?
Research on HIFU actually began in the 1950s at Indiana University. In 1994, the first human prostate cancer study was done by Dr. Marberger and Madersbacher at the Univ. of Vienna in Austria using the now Sonablate® 200 treating 29 human prostates in vivo shortly before performing a radical prostatectomy. The goal was to see if the energy delivered was enough to destroy the desired tissue. The study found that treatment could be performed safely and could be repeated. In 1995, a study done at IU showed that the whole prostate could be treated without damaging the prostate capsule or the rectal wall. In 1999, Dr. Toyaki Uchida began treating patients using the Sonablate® 200. In 2001, Sonablate® 500 receives CE mark from Europe and the first patient in the study was treated at IU by Dr. M. Koch. In 2004, USHIFU was created and has placed machines in Canada, Mexico, Costa Rica, South Africa and the Caribbean. Currently there are nearly 100 Sonablate® 500 HIFU centers worldwide on six continents. There are over 150 physicians using the Sonablate® 500 worldwide and over 5,000 total procedures have been completed with the Sonablate®.

2. Where can I find HIFU data and statistics?
To read clinical papers, abstracts and data visit our clinical data section where you can download the latest published data and reports. Learn more about the Benefits of HIFU with the Sonablate® 500.

3. Does HIFU only treat the cancerous cells or does it ablate the entire prostate?
HIFU treated the entire prostate by targeting tissue in overlapping treatment zones. The tissue is heated rapidly in small lesion until eventually the entire prostate is ablated. By treating the entire prostate gland, the chance for recurrence, or the cancer coming back is minimized. All the organs and tissue outside of the prostate remain unaffected during HIFU.

4. If the entire prostate is treated, does that include the urethra? What happens to the uretha? Is it damaged?
The urethra consists of different anatomical segments. From the tip of the penis to the base of the bladder: the fossa navicularis, the pendulous urethra, the membranous urethra and the prostatic urethra. During HIFU, the entire prostate is ablated, including the prostatic urethra, as it can have cancerous cells in it. In doing so the end result is an empty cavity that acts like a conduit during normal urination. However, the urethra is derived from a different type of tissue (derived from the bladder squamous type epithelium) vs. prostatic tissue (glandular, fibrotic and muscular) and regenerates/re-epithelializes with time. The sphincter and bladder neck are the vital structures with respect to maintenance of urinary function NOT the urethra. These vital structures are not affected or harmed during HIFU.